Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.
نویسندگان
چکیده
Administration of[3H]aflatoxin B2 (2,3-dihydroaflatoxin B1)(AFB2) to male rats resulted in levels of hepatic DNA- and ribosomal(r)RNA-aflatoxin adducts that were about 1% of those for rats given [3H]aflatoxin B1(AFB1). The levels of hepatic protein-aflatoxin adducts were 35 to 70% as great for AFB2-treated as compared to AFB1-treated rats...
منابع مشابه
Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.
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ورودعنوان ژورنال:
- Cancer research
دوره 37 1 شماره
صفحات -
تاریخ انتشار 1977